Registered Nurse jobs in South Carolina
79 openings from the last 45 days, updated daily.
Registered Nurse pay and hiring in South Carolina
| 25th percentile | Median | 75th percentile |
|---|---|---|
| $72,332 | $98,269 | $112,289 |
Midpoints of the pay ranges posted in 75 current Registered Nurse listings in South Carolina, per year. That is 9% below the national median of $108,004 for Registered Nurse listings.
Employers hiring the most in South Carolina
- Prisma Health (15)
- Genie Healthcare (7)
- Veterans Health Administration (3)
- TRS Healthcare (2)
- Medical University of South Carolina (2)
- Encompass Health Rehabilitation Hospital of Irmo (2)
- HCA Healthcare (2)
- Voca Healthcare (2)
- Piedmont Healthcare (2)
- Prisma Health Greenville Memorial Hospital (2)
Most openings by city: Travelers Rest (11) and Sumter (10).
- Travel Med Surg / Telemetry RN - Nights - $2,818 per week
- Travel Med Surg / Telemetry RN - Nights - $2,493 per week
- Travel Cardiac Telemetry RN - $2,692 per week
- Registered Nurse (RN) - Acute Care, Intermediate ICU, IICU, FT, Days
- Travel Nurse RN - Med Surg / Telemetry - $1,784 per week
- Travel ER RN - $2,606 per week
- Registered Nurse (RN) - Clinic Coordinator, Heart Failure Clinic, FT, Days
- Operating Room Registered Nurse (OR RN)
- Travel Med Surg / Telemetry RN - $1,878 per week
- Travel Telemetry RN (Registered Nurse) in Lexington, KY - 1167086
- Registered Nurse II - Dialysis- PRN
- Dialysis Registered Nurse
- Travel ICU RN - $2,377 per week
- Registered Nurse (Asst/Assoc/Deputy Chief)
- Local Contract Med Surg/Telemetry Float RN - $43-47 per hour
- Registered Nurse (RN) - Acute Care, Short Stay Surgical, PRN, Days
- Registered Nurse (RN)-Acute Care, Nephrology, PT, Days
- Registered Nurse (RN)-Acute Care, Intensive Care Unit, FT, Nights
- Registered Nurse (RN)-Acute Care, Facility Resource Pool, Critical Care, Part Time, Days
- Registered Nurse (RN)-Acute Care, Emergency Department, FT, Nights
- Registered Nurse (RN)-Acute Care, Nephrology, FT, Variable
- Registered Nurse (RN)-Acute Care, Facility Resource Pool, Critical Care, FT, Days
- Registered Nurse (RN)-Acute Care, Surgical Inpatient, FT, Nights
- Registered Nurse (RN) Acute Care, Nephrology, FT, Days
- Registered Nurse (RN)-Acute Care, Labor and Delivery, PRN, Variable
- Registered Nurse (RN)-Acute Care, Facility Resource Pool, PT, Days
- Hospice RN Clinical Manager
- Registered Nurse
- Travel Rehab RN - $1,852 per week
- Travel MS/Tele RN - $1,927 per week
- Travel Cardiac Tele RN - $1,978 per week
- RN - Tele
- Travel Cardiac Tele RN - $2,634 per week
- Registered Nurse (RN) - Emergency Department (ED) Float Pool - St. Francis Downtown - PRN
- Registered Nurse
- Float Pool Registered Nurse PRN
- RN Clinical Manager Home Health
- Travel Nurse RN - Endoscopy in Manning, SC
- Nursing Supervisor (RN) - CV ICU
- RN - 38537041
- Travel MS/Tele RN - $1,924 per week
- Travel Med Surg / Tele RN - $1,924 per week
- Travel Cardiac Tele RN - $1,757 per week
- Licensed Practical Nurse (LPN) / Registered Nurse (RN) - Pediatric Home Health
- Hospice RN Administrator I
- Registered Nurse
- Travel Nurse RN - Labor & Delivery - $2,163 per week in Florence, SC
- Registered Nurse (RN) - Cardiac Catheterization Laboratory
- RN - 38453526
- Registered Nurse (RN) - Post-Anesthesia Care Unit (PACU) - Berkeley Hospital
- Travel Nurse RN - Labor and Delivery - $2,560 per week
- Travel Nurse RN - Orthopedics - $1,784 per week
- Travel Nurse RN - Telemetry - $1,884 per week
- Travel Cardiac Tele RN - $2,040 per week
- Registered Nurse (RN) / Travel / Medical / Telemetry
- ICU RN
- Registered Nurse
- RN - Pacu
- Registered Nurse - PRN
- Travel ICU RN - $2,338 per week
- RN Admission-Discharge
- RN Case Manager - Hospice, Aiken, SC
- RN - MedSurg/Tele
- Registered Nurse I (new graduate) - ART 6W Acute Care
- RN - Labor and Delivery
- Travel Registered Nurse RN Telemetry
- Travel Med Surg Tele RN - $1,924 per week
- Registered Nurse Hospice
- Dialysis Clinical Coordinator (Registered Nurse)
- Registered Nurse (RN) - Acute Care, PACU, Full Time, Variable
- Registered Nurse (RN) - Nurse Resident, Winter 2027, Moultrie Suite, Heart Failure/LVAD Acute Care
- Travel Pediatric Registered Nurse - $1,865 per week
- RN Agency Nurse Port Royal South Carolina - Up to $52.00/Hr
- RN - Cvor
- Travel CVOR RN - $2,737 per week
- Travel Cardiac Tele RN - $1,996 per week
- RN - Hospice Augusta- Aiken, SC
- Travel MS/Tele RN - $1,868 per week
- Registered Nurse Assistant Nurse Manager
Registered Nurse jobs in South Carolina FAQ
How much do Registered Nurse jobs pay in South Carolina?
Across 75 current Registered Nurse listings in South Carolina that post pay, the median is $98,269 per year. The middle half of listings pay between $72,332 and $112,289. That is 9% below the national median of $108,004 for Registered Nurse listings.
Who is hiring for Registered Nurse jobs in South Carolina?
The employers with the most current Registered Nurse openings in South Carolina are Prisma Health, Genie Healthcare, Veterans Health Administration, TRS Healthcare and Medical University of South Carolina.
Which cities in South Carolina have the most Registered Nurse jobs?
The most current Registered Nurse openings in South Carolina are in Travelers Rest (11) and Sumter (10).
How do I apply for Registered Nurse jobs in South Carolina?
Reach lists 79 Registered Nurse openings in South Carolina posted in the last 45 days, the newest on November 12, 2026. Each opening links to its original posting, where you can apply directly. Reach can also tailor your resume and cover letter to each opening and apply for you. It is free to start.
Guides for your search
- Contract vs full-time pay: break even
Convert contract offers to a salary, include benefits and taxes, and see the break-even hourly rate you need to match a full-time job.
- Write a post-interview thank-you email that works
A quick guide to writing a post-interview thank-you email that stands out, adds value, and can sway a close hiring decision.
- Career-change resume blueprint - CareerGuide
A step-by-step guide to a career-change resume that puts the new role front-and-center, using a hybrid format and skill-focused bullets.
All occupations › Registered Nurse › South Carolina